Human Rena-strip Kit, 25 tests

$433.60

Rating: SKU: H-RENA-LF-025. Category: Tags: ,

The Rena-strip test is a “Research Use Only” single-use, qualitative, or quantitative (with reader), lateral flow assay for the detection of KIM-1 in human urine.

Product Description

KIM-1 is a type I trans-membrane structural glycoprotein located in the renal proximal tubule epithelial cells.  These cells undergo regeneration after various forms of injury and shed KIM-1 antigen into the urine.  Thus, urinary KIM-1 is an early and specific biomarker for tubular kidney injury.  KIM-1 has become widely recognized by many organizations and agencies, including the FDA, as an excellent biomarker in pre-clinical studies to monitor acute kidney tubular toxicity by identifying adverse reactive drugs and therapeutic agents in drug development.

Kidney injury caused by therapeutic agents and drug induction is a common type of injury requiring appropriate monitoring and intervention.  Current standards using blood urea nitrogen and creatinine are considered late indicators of kidney injury and are often non-specific.  KIM-1 has been shown continually to outperform traditional biomarkers of kidney injury in preclinical biomarker studies. The detection of KIM-1 can occur in as little as six hours post injection of an agent known to cause kidney injury.

The Human Rena-strip test is a 15-minute qualitative (or quantitative with optional reader) lateral flow assay. Human urine samples are added to the cassette and results can be read within 15 minutes.

Specifications:

Kit Contents:

  • Human Rena-strip cassettes in white foil pouches with dessicant, 25 cassettes

Storage Temperature: Store at room temperature.

Shipping Temperature: Ambient

Stability: 2 years from date of manufacture

Product is for research use only.

Additional information

Weight 2 lbs
Dimensions 7 x 5 x 4.5 in

Documents

Product Flyer – Assays for KIM-1 Acute Kidney Injury Biomarker

Product Insert – H-RENA-LF-025

 

References

  1. Vesna D Stojanović, Nenad A Barišić, Nada M Vučković, Aleksandra D Doronjski, Amira E Peco Antić. Urinary kidney injury molecule-1 rapid test predicts acute kidney injury in extremely low-birth-weight neonates. Pediatric Research. 2015; 78:430-435.